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This is randomized, double-blind, placebo-controlled study of the long-term efficacy, safety, and tolerability of multiple doses of aleniglipron in participants living with overweight or obesity and T2DM. Participants will be randomized to aleniglipron or placebo for a total of 76 weeks of treatment.

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 74 sites in total · contact listed

The objective of this registry is to gather clinical data on symptomatic patients with mitral valve disease, including patients with mitral regurgitation, mitral stenosis, and mixed mitral valve disease. Data collected from this registry are expected to improve our understanding of the impact of cor…

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 24 sites in total · contact listed

This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy and immunotherapy (chemo-immunotherapy) for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. Inotuzumab ozogamicin is a monoclonal antibody, which is a type of protei…

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 231 sites in total · contact listed

This phase III trial compares the combination of four drugs (daratumumab, bortezomib, lenalidomide and dexamethasone) to the use of a three drug combination (daratumumab, lenalidomide and dexamethasone). Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell g…

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📍 Nearest site: Kingman, Kansas, United States — 28 km away · 647 sites in total

Study GSBR-1290-12 is a Phase 3 pivotal, multicenter, global, randomized, placebo-controlled, double-blind study to investigate the long-term efficacy, safety, and tolerability of 3 maintenance doses of aleniglipron once daily (QD) compared with placebo, when used in combination with a reduced-calor…

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 71 sites in total · contact listed

The objective of this study is to establish the safety and effectiveness of the Edwards SAPIEN X4/X4S Transcatheter Heart Valve (THV) in subjects who are at high or greater risk with a failing aortic bioprosthetic valve.

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 36 sites in total

The primary purpose of this study is to evaluate the safety, tolerability, and efficacy of SYNC-T Therapy SV-102 and to identify the maximum tolerated dose (MTD) and/or selected dose for phase 2b study.

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 23 sites in total

The purpose of the study is to evaluate the safety, tolerability, and efficacy of the two different treatment combinations of tulmimetostat in participants with de novo or recurrent Metastatic Hormone-Sensitive Prostate Cancer (mHSPC).

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 31 sites in total · contact listed

This study will evaluate the immunogenicity, safety, and tolerability of rF1V-1018 vaccine

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📍 Nearest site: El Dorado, Kansas, United States — 85 km away · 4 sites in total

The purpose of this study is to evaluate the safety, efficacy, and PK of Vibegron in pediatric participants with NDO who are regularly using CIC

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 38 sites in total · contact listed

The purpose of this study is to evaluate the efficacy, safety, and tolerability of Suzetrigine (SUZ) in participants with pain associated with diabetic peripheral neuropathy (DPN).

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 76 sites in total

The purpose of this study is to evaluate safety, effect on cramps, function and quality of life of ranolazine versus placebo for the treatment of ALS.

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 6 sites in total · contact listed

This is a 26-week, multi-center, randomized, double-blind, placebo-controlled study with a 4-week treatment-free Safety Follow-up period to assess the safety and efficacy of tenapanor (5 mg, 25mg, and 50 mg) in adult patients with Chronic Idiopathic Constipation (CIC) when administered twice daily f…

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 109 sites in total · contact listed

This phase III trial compares the effect of adding immunotherapy (brentuximab vedotin and nivolumab) to standard treatment (chemotherapy with or without radiation) to the standard treatment alone in improving survival in patients with stage I and II classical Hodgkin lymphoma. Brentuximab vedotin is…

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 415 sites in total · contact listed

The goal of this clinical trial is to learn if pridopidine can slow the clinical decline of Huntington's Disease (HD) in adult participants. It will also inform about the safety of pridopidine. The main questions the study aims to answer are: Does pridopidine slow the overall worsening of HD over…

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 66 sites in total · contact listed

This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that has spread outside of the lungs (stage IIIB-IV) and has a change (mutation) in a gene called EGFR. The EGFR protein is involved in cell signa…

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 603 sites in total · contact listed

The purpose of this study is to evaluate the efficacy, safety, and tolerability of elecoglipron compared with oral semaglutide in adults with T2DM and increased cardiovascular risk that is inadequately managed alone or on stable treatment with other background glucose-lowering medication(s).

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 209 sites in total

A phase 3b, Randomized, Controlled Trial of Nadofaragene Firadenovec vs. Observation in Participants with Intermediate Risk Non-Muscle Invasive Bladder Cancer (IR NMIBC)

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 107 sites in total

The study is an early feasibility study to measure individual patient clinical outcomes and effectiveness, evaluate the safety and function of the DUO Transcatheter Tricuspid Coaptation Valve System (DUO System).

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 15 sites in total · contact listed

The purpose of this study is to assess how well-tolerated GSK's investigational varicella vaccine (VNS Vaccine) is, in comparison to an already approved varicella vaccine (VV) known as Varivax. The study will be conducted on healthy children aged 12 to 15 months, and who have neither contracted vari…

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📍 Nearest site: El Dorado, Kansas, United States — 85 km away · 46 sites in total

The purpose of this study is to generate clinical evidence on valve safety and performance in subjects treated by redo Transcatheter Aortic Valve Replacement (TAVR).

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 71 sites in total · contact listed

This screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and accruing simultaneously to a multi-sub-study hybrid Master Protocol (Lung-MAP). The type of cancer trait (biomarker) will deter…

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📍 Nearest site: Kingman, Kansas, United States — 28 km away · 1,229 sites in total

This phase III trial tests how well the addition of dinutuximab to Induction chemotherapy along with standard of care surgical resection of the primary tumor, radiation, stem cell transplantation, and immunotherapy works for treating children with newly diagnosed high-risk neuroblastoma. Dinutuximab…

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 179 sites in total · contact listed

This phase III trial studies how well active surveillance help doctors to monitor subjects with low risk germ cell tumors for recurrence after their tumor is removed. When the germ cell tumor has spread outside of the organ in which it developed, it is considered metastatic. Chemotherapy drugs, such…

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 629 sites in total · contact listed

The purpose of the study is to evaluate the clinical safety and efficacy of the Prevail DCB.

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📍 Nearest site: Wichita, Kansas, United States — 43 km away · 51 sites in total · contact listed